What is the difference between paraganglioma and pheochromocytoma?
Pheochromocytoma and paraganglioma are rare tumors that come from the same type of tissue. Pheochromocytoma is a rare tumor that forms in the adrenal medulla (the center of the adrenal gland). Paragangliomas form outside the adrenal gland.
What causes pheochromocytoma and paraganglioma?
Pheochromocytomas/paragangliomas may be caused by mutations of one of at least ten different genes: the RET gene, which is also associated with multiple endocrine neoplasia type 2; the VHL gene, which is also associated with von Hippel-Lindau syndrome; the neurofibromatosis (NF1) gene, associated with neurofibromatosis …
What is pheochromocytoma Wikipedia?
Pheochromocytoma (PHEO or PCC) is a rare tumor of the adrenal medulla composed of chromaffin cells, also known as pheochromocytes. When a tumor composed of the same cells as a pheochromocytoma develops outside the adrenal gland, it is referred to as a paraganglioma.
Is paraganglioma a cancer?
Paragangliomas are usually noncancerous (benign). But some paragangliomas can become cancerous (malignant) and spread (metastasize) to other parts of the body. Paragangliomas are rare tumors. They can occur at any age, but they’re most often diagnosed in adults between 30 and 50.
What causes pheochromocytoma to grow?
A pheochromocytoma is a tumor in the adrenal gland. It causes the gland to make too much of the hormones epinephrine and norepinephrine. This tumor usually occurs when you are in your 30s, 40s, or 50s. It happens to both men and women.
What does a pheochromocytoma do?
If you have a pheochromocytoma, the tumor releases hormones that may cause high blood pressure, headache, sweating and symptoms of a panic attack. If a pheochromocytoma isn’t treated, severe or life-threatening damage to other body systems can result.
What is paraganglioma?
Paraganglioma is a type of neuroendocrine tumor that forms near certain blood vessels and nerves outside of the adrenal glands. The adrenal glands are important for making hormones that control many functions in the body and are located on top of the kidneys.
Which hormones are produced by a pheochromocytoma?
What type of cancer is pheochromocytoma?
Pheochromocytoma is a type of neuroendocrine tumor that grows from cells called chromaffin cells. These cells produce hormones needed for the body and are found in the adrenal glands. The adrenal glands are small organs located in the upper region of the abdomen on top of the kidneys.
Is pheochromocytoma slow growing?
Pheochromocytomas usually grow slowly. A pheochromocytoma is called a primary adrenal gland tumor because it starts inside an adrenal gland. Read about other types of primary adrenal gland tumors.
Are pediatric patients diagnosed with pheochromocytoma and paraganglioma diagnosed in France since 2000?
Purpose: The purpose of this work is to assess the clinical outcome of pediatric patients diagnosed with pheochromocytoma and paraganglioma (PPGL) detected in France since 2000. Methods: A retrospective multicenter study was conducted that included all patients younger than 18 years with PPGL diagnosed in France between 2000 and 2016.
What is the difference between pheochromocytoma and paraganglioma?
Pheochromocytoma and paraganglioma are related tumors that differ mainly in location; pheochromocytomas are adrenal, and paragangliomas can be anywhere else. The symptoms are protean and common, but the tumors are rare.
What is a pheochromocytoma?
When the same type of tumor is found in the adrenal gland, they are referred to as a pheochromocytoma. They are rare tumors, with an overall estimated incidence of 1/300,000.
What is the PMC for paraganglioma (extra-adrenal pheochromocytoma)?
PMC 5854189. PMID 28746746. ^ “Metastatic catecholamine-secreting paraganglioma (extra-adrenal pheochromocytoma)”. The American Journal of Medicine. 61 (4): 523–532.