What are new alternative methods of animal testing?
Test methods that incorporate the 3Rs are referred to as new alternative methods. Under U.S. law and policies, scientists must consider alternative methods before using animals for toxicology research and testing.
Can we replace animal testing with testing on humans?
The replacement of animal testing with testing on humans comes with its own set of ethical and technical issues. Technically the issues include differences in how different people react to different chemicals and processes.
What animals are used for animal testing?
Most of the vertebrates animals prone to be used in animal testing are guinea pigs, dogs, monkeys, rabbits, and rats. However, recent studies have shown that the use of different organisms can replace experimental animals. The following table shows some of the alternative organisms.
Can read-across replace animal testing?
This mapping out of chemicals and chemical compounds has been used to replace animal testing before and is known as read-across. Previously it has relied on researchers to analyze and evaluate the chemicals which is time-consuming and, to some extent, subjective.
How to overcome the drawbacks of animal testing?
Various alternatives to animal testing were proposed to overcome the drawbacks associated with animal experiments and avoid the unethical procedures. A strategy of 3 Rs (i.e. reduction, refinement and replacement) is being applied for laboratory use of animals. Different methods and alternative organisms are applied to implement this strategy.
Is computer-aided drug design an alternative to animal testing?
Vedani A. Computer-aided drug design: an alternative to animal testing in the pharmacological screening. ALTEX. 1991;8:39. [PubMed] [Google Scholar]