Does giant cell tumor recur?
Clinically, GCT presents as a benign but often aggressive lesion with a tendency toward local recurrence. Depending on the type of treatment and the local presentation of the tumor, recurrence rates range from 0% to 65% (Table 1) [1, 3, 5, 6, 15, 20, 25, 26, 29, 31, 37, 38, 40, 43, 50].
Can giant cell tumor spread?
While giant cell tumors are typically benign (noncancerous), they can grow quickly and destroy bone close to a joint. In rare cases, a giant cell tumor may spread, or metastasize, to the lungs.
What is the most common site for giant cell tumors?
Key points about giant cell tumors Most occur in the long bones of the legs and arms. Giant cell tumors most often occur in young adults when skeletal bone growth is complete.
How fast do giant cell tumors grow?
Giant cell tumor of bone (GCTB) in skeletally immature patients is rare, and little is known regarding how fast GCTB can grow. We report a case of a 10-year-old skeletally immature girl with pathologically proven GCTB with obvious growth plate invasion that showed surprisingly rapid growth over only 14 days.
What does recurrence rate mean?
The rate at which something, especially a disease or medical condition, recurs or returns (after treatment).
Can chondroblastoma become malignant?
Malignant Chondroblastoma The term “malignant” denotes its metastatic potential and aggressive behavior rather than histological malignancy. Approximately 2% of benign chondroblastoma do metastasis to the lung. The metastatic lesion in lung carries similar morphology of being benign as well.
Is giant cell tumor life threatening?
Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations.
What is giant cell tumor?
What is Giant Cell Tumor? Giant cell tumors are rare, aggressive, non-cancerous tumors. They usually develops near a joint at the end of the bone. Symptoms include a visible mass, bone fracture, swelling, and pain. Treatments for giant cell tumors depend on many factors such as age, health, and the extent of the disease.
What are giant cell tumors?
Summary. A giant cell tumor (GCT) of bone is a benign (noncancerous) bone tumor that typically develops near the joints of the knee,wrist,shoulder,or spine.
What causes giant cell tumor of the tendon sheath?
Etiology. As is true for most soft-tissue tumors, the etiology of giant cell tumors of the tendon sheath is unknown. Pathogenetic theories have included trauma, disturbed lipid metabolism, osteoclastic proliferation, infection, vascular disturbances, immune mechanisms, inflammation, neoplasia, and metabolic disturbances.
Are giant cell tumors cancerous?
Giant cell tumors are rare tumors that develop when many benign (noncancerous) cells group together and form a large mass. The concern with giant cell tumors is that they can spread to other areas of the body and become cancerous tumors. Giant cell tumors usually form in bones and are most often found in the knee.