What is 2-deoxy-D-glucose?

?) 2-Deoxy-d-glucose is a glucose molecule which has the 2- hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis.

What is the function of 2 deoxy-D glucose?

2-Deoxy- D -glucose. 2-Deoxy-D-glucose is a glucose molecule which has the 2- hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis. As such; it acts to competitively inhibit the production of glucose-6-phosphate from glucose at the phosphoglucoisomerase level (step 2 of glycolysis).

What is the IUPAC name for deoxyglucose?

2-Deoxy- d -glucose. #N#Names. IUPAC name. (4 R ,5 S ,6 R )-6- (hydroxymethyl)oxane-2,4,5-triol. Other names. 2-Deoxyglucose. 2-Deoxy- d -mannose.

Can 2-deoxy-D-glucose be used as a radio-modifier to improve radiotherapy?

Experimental studies (both in vitro and in vivo) have shown that 2-deoxy-D-glucose (2-DG), a glucose analog and glycolytic inhibitor, enhances radiation-induced damage selectively in tumor cells while protecting normal cells, thereby suggesting that 2-DG can be used as a differential radio-modifier to improve the efficacy of radiotherapy.