What does CGD mean?

» CGD stands for Chronic Granulomatous Disorder. It is a life-threatening and life-limiting condition. » CGD is an inherited genetic disorder. » It used to be known as Chronic Granulomatous Disease and doctors sometimes still use this name.

Can granulomatous disease be cured?

Treatment consists of continuous therapy with antibiotic and antifungal medications to treat and prevent infections. The only cure for the disease is an allogeneic hematopoietic stem cell transplantation (HSCT).

Who treats granulomatous disease?

Chronic granulomatous disease (CGD) specialists, usually immunologists, infectious disease physicians, hematologists, and oncologists, have expertise in treating CGD.

Do I have CGD?

Signs and symptoms of CGD usually appear early in childhood and very uncommonly are diagnosed in adults. They can include: Recurrent infections caused by bacteria and fungi. Abscesses in the liver, lungs, skin or spleen.

How do you get CGD?

Autosomal recessive CGD occurs when both parents pass on a faulty gene to their child. In autosomal recessive, both parents are carriers of CGD. They have 1 normal copy of the gene and 1 copy of the gene that doesn’t work right. But the most common way CGD is inherited is X-linked.

How common is CGD?

CGD is not common. Doctors diagnose it in about 1 out of every 200,000 to 250,000 people worldwide. CGD occurs more often in males than in females.

Is CGD fatal?

Ear infections and skin infections from swimming pools and hot tubs are typically mild. Severe infections can be fatal if not treated right away.

Is CGD curable?

Chronic use of antibiotics may be used to prevent infections. A medicine called interferon-gamma may also help reduce the number of severe infections. Surgery may be needed to treat some abscesses. The only cure for CGD is a bone marrow or stem cell transplant.

How is actimmune administered?

ACTIMMUNE® (Interferon gamma-1b) should be administered subcutaneously 3 times weekly. It can be injected by the patient or caregiver after appropriate training by a healthcare professional.